Multiplexing Homocysteine in Primary Newborn Screening Assays Using Maleimides as Select Derivatization Agents
Homocystinuria (HCU), a group of inherited disorders, causes symptoms ranging from failure to thrive and developmental delays in infants or young children to abnormal blood clots with onset in adults.1 Approximately 1 in 200,000 to 335,000 people have HCU globally.2