Potentiating Antibody Therapy by Targeting Complement Deposited on Cancer Cells
Humanized Murine Monoclonal Antibodies That Neutralize Type-1 Interferon (IFN) Activity
Human Salivary Gland Cell Lines for Propagation of Enteric Viruses
Cloned Genomes Of Infectious Hepatitis C Virus And Uses Thereof
Methods for Using Modulators of Extracellular Adenosine or an Adenosine Receptor To Enhance Immune Response and Inflammation
Peptide Mimotope Candidates for Otitis Media Vaccine
Interleukin 24 (IL-24) to treat inflammatory diseases
Proinflammatory T-helper 17 cells (Th17) play important roles in host immune defense against infection, but uncontrolled activation of these cells, known as the Th17 response, may cause autoimmune and autoinflammatory diseases (uveitis, multiple sclerosis, rheumatoid arthritis, and Crohn’s disease) through the effects of Th17 lineage cytokines (such as, IL-17F, IL-22 and GM-CSF). Importantly, IL-17A (a proinflammatory cytokine) represses other Th17 lineage cytokines by upregulating the regulatory cytokine IL-24.
Surgical Tool for Sub-retinal Tissue Implantation
The accurate placement of transplanted tissue at a precise position in the retina is difficult but critical for a successful implementation of an ocular surgical intervention.
Reporter Assay for Detection and Quantitation of Replication-Competent Gammaretrovirus
Gammaretroviral vectors were the first viral gene-therapy vectors to enter clinical trials and remain in use. One potential hazard associated with the use of such vectors is the presence of replication-competent retroviruses (RCR) in the vector preparations – either as a result of: 1) recombination events between the plasmids used for vector production, 2) interactions between the plasmids and endogenous retroviral sequences in the packaging cell lines, or 3) as a result of contamination in the laboratory.