Low-Cost, Temperature Tolerant Rotavirus Vaccine For Use in Developing Countries

Rotavirus is a disease that affects nearly every child worldwide. While most cases have mild symptoms, it is responsible for one third of infant hospitalizations for severe diarrhea and kills an estimated 200,000 children a year, mostly in developing countries. Researchers at the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH) developed vaccine formulations to address the six most common forms of rotavirus.

Low-Cost, Temperature Tolerant Rotavirus Vaccine For Use in Developing Countries

Rotavirus is a disease that affects nearly every child worldwide. While most cases have mild symptoms, it is responsible for one third of infant hospitalizations for severe diarrhea and kills an estimated 200,000 children a year, mostly in developing countries. Researchers at the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH) developed vaccine formulations to address the six most common forms of rotavirus.

Gardasil™: A New Era in Cancer Prevention

Human papilloma virus (HPV) is the most common sexually transmitted infection in the United States. The Centers for Disease Control and Prevention estimates that about 6.2 million Americans are infected with genital HPV each year and that over half of all sexually active men and women become infected at some time in their lives. While most HPV infections are cleared by the body’s own defense system and do not lead to cancer, virtually all cases of cervical cancer are linked to HPV infection.

PROSTVAC, a Therapeutic Vaccine for Treating Prostate Cancer

Prostate cancer is the most common non-skin cancer of males in the U.S., and is responsible for more deaths than any other cancer, except lung cancer. Cancer vaccines, which harness the body’s immune system to identify and destroy cancer cells, have emerged as a promising new approach to fighting prostate cancer. One approach to cancer vaccination involves identifying antigens from cancer cells and immunizing cancer patients against those antigens to stimulate the body’s immune cells to attack and kill the cancer cells. 

Development of First Immunotherapy to Treat Chordoma, a Rare Bone Cancer

Cancer vaccines harness the immune system to identify and destroy cancer cells, and are a promising new approach to fighting cancer. In contrast to preventative vaccines, cancer vaccines identify antigens from cancer cells and immunize cancer patients against those antigens to stimulate the body’s immune cells to attack and kill the cancer cells. The National Cancer Institute (NCI) has developed investigational cancer vaccines that induct a specific, targeted immune response against cancer cells expressing the brachyury protein.

Development of First Immunotherapy to Treat Chordoma

Cancer vaccines harness the immune system to identify and destroy cancer cells, and are a promising new approach to fighting cancer. In contrast to preventative vaccines, cancer vaccines identify antigens from cancer cells and immunize cancer patients against those antigens to stimulate the body’s immune cells to attack and kill the cancer cells. The National Cancer Institute (NCI) has developed investigational cancer vaccines that induce a specific, targeted immune response against cancer cells expressing the brachyury protein.