Hybridoma cell line 715 expresses monoclonal antibody specific for Moloney murine leukemia virus (MuLV) gp70. Details may be found under NIH AIDS Reagent Program Catalog Number 1278: https://www.beiresources.org/Catalog/BEICellLinesUninfected/ARP-1278.aspx .
Hybridoma cell line 273 expresses monoclonal antibody specific for murine leukemia virus (MuLV) gp70. Details may be found under NIH AIDS Reagent Program Catalog Number 1279: https://www.beiresources.org/Catalog/BEICellLinesUninfected/ARP-1279.aspx .
Hybridoma cell line 500 expresses monoclonal antibody specific for Moloney murine leukemia virus (MuLV) gp80. Details may be found under NIH AIDS Reagent Program Catalog Number 1277: https://www.beiresources.org/Catalog/BEICellLinesUninfected/ARP-1277.aspx .
Available for nonexclusive licensing for research uses is the cell line, SV-k1, derived from the Organ of Corti. The line was developed from the stria vascularis, an organ localized on the lateral wall of the cochlea, adjacent to the Organ of Corti, containing cell populations specialized in the production of an endolymph very rich in K+ characteristic of the mammalian inner ear.
The technology discloses composition of compounds that are highly selective P2Y14 receptor antagonists,
with moderate affinity with insignificant antagonism of other P2Y receptors. These compounds might provide a
treatment for patients for various disease conditions, including lung inflammation, kidney inflammation,
asthma, diabetes, obesity, and neuropathic pain of diverse states. In vivo data using mouse lines with the
receptor knocked out in specific tissues showed that P2Y14 receptor antagonists act on adipocytes to improve
Tumor-specific mutated proteins can create neoepitopes, mutation-derived antigens that distinguish tumor cells from healthy cells, which are attractive targets for adoptive cell therapies. However, the process of precisely identifying the neoepitopes to target is complex and challenging. One method to identify such neoepitopes is Mass Spectrometry (MS) when used in conjunction with elution of peptides bound to a specific Human Leukocyte Antigen (HLA) allele.
Summary:
The National Cancer Institute (NCI) has identified HLA-A11:01-restricted T Cell Receptors (TCRs) targeting the KRAS G13D mutation. The NCI seeks licensees for the use of these TCRs in research.
Description of Technology:
Summary:
The National Cancer Institute seeks research co-development partners and/or licensees for a standardized method of detecting T-cell receptor (TCR) cross-reactivity as a means of proving safety and efficacy in preclinical evaluations ahead of clinical trials.
Description of Technology:
Porcine enteric calicivirus (PEC) is a member of the genus Sapovirus in the family Caliciviridae. This virus causes diarrheal illness in pigs, and is presently the only enteric calicivirus that can be grown in cell culture. In addition to its relevance to veterinary medicine as a diarrheal agent in pigs, PEC serves as an important model for the study of enteric caliciviruses that cause diarrhea and that cannot be grown in cell culture (including the noroviruses represented by Norwalk virus).