Improved Botulism, Botulinum Neurotoxin Type-E Diagnostics

CDC researchers have improved upon a prior, HHS patented mass spectrometry-based Endopep-MS assay that is able to rapidly detect and differentiate all seven botulinum neurotoxin (BoNT) types A to G. This current improvement comprises the addition of two optimized substrate peptides that increases the assay's sensitivity,relative to prior substrates, for botulinum neurotoxin type-E (BoNT/E) by greater than 100 fold.

Multiplexing Homocysteine in Primary Newborn Screening Assays Using Maleimides as Select Derivatization Agents

Homocystinuria (HCU), a group of inherited disorders, causes symptoms ranging from failure to thrive and developmental delays in infants or young children to abnormal blood clots with onset in adults.1 Approximately 1 in 200,000 to 335,000 people have HCU globally.2

Sound Attenuation Canopy

High sound levels in work settings can have negative effects on worker concentration and productivity. Even offices separated by walls and doors transmit sound between them. As office buildings optimize space, the allotment for each person, office, or work area often decreases. With more office workers in a given area, localized noise levels are increasing beyond optimal levels for worker productivity. 

Sound Attenuation Canopy

High sound levels in work settings can have negative effects on worker concentration and productivity. Even offices separated by walls and doors transmit sound between them. As office buildings optimize space, the allotment for each person, office, or work area often decreases. With more office workers in a given area, localized noise levels are increasing beyond optimal levels for worker productivity.