Green Team Efforts - NIH Office of Technology Transfer

The Office of Technology Transfer (OTT) implemented office-wide efforts in recycling, energy reduction and creating a paperless office. OTT procured recycling bins for paper, batteries, mail packages, printer toner, glass and plastic. When drafting documents, the office uses old paper and, when possible, prints on both sides of the paper before recycling. During the most recent office renovation, OTT installed motion-sensing light switches to all its renovated office spaces. 

Therapeutic Immunotoxins for the Treatment of T Cell Malignancies

Abnormal T lymphocyte (T cell) function, including tumor formation in T cells, can lead to a wide variety of diseases. Over 100 million people worldwide suffer from T cell autoimmune disorders of varying severity, such as lupus and graft-versus-host disease, and the incidence of T cell-mediated cancers, including lymphomas and leukemias, has risen over the past decade. These diseases can be deadly, and not all patients respond to standard therapies.

A Lifesaving Diagnostic Test for Cancer Patients

Most people are aware that anti-cancer treatments often have negative side effects, but patients are willing to tolerate these side effects for the potential life-saving effects of the treatment. However, some patients treated with the anti-cancer drug 5-Fluorouracil (5-FU) will have fatal reactions typically caused by cardiotoxicity. A life-saving diagnostic test to identify cancer patients who may experience 5-FU toxicity has been developed by scientists at the National Cancer Institute (NCI).

Dr. Samuel Bish - Licensing and Patenting Manager, NIH Office of Technology Transfer

Technology Transfer Professional Rookie of the Year

The structure and function of the Office of Technology Transfer (OTT) at the National Institutes of Health (NIH) require new Licensing and patenting managers to be involved in all aspects of technology transfer, specifically technology valuation, patent prosecution, license negotiation, marketing of technologies, and the review of Cooperative Research and Development Agreements (CRADAs). 

Use of Therapeutic Antibodies as a Novel Treatment for Multiple Sclerosis

Multiple sclerosis (MS) is a disease of the central nervous system in which the immune system attacks the brain and spinal cord, typically resulting in muscle weakness, problems with vision and coordination, pain, and, in some patients, cognitive impairments. The disorder affects approximately 400,000 people in the U.S. and more than 2.5 million people worldwide. Patients with relapsing forms of MS are currently treated with one of three FDA-approved interferon-beta agents or with glatiramer acetate.

Vibro-Tactile Stimulation Device and Method for Swallowing Disorder

The transferred technology is a non-invasive, intensive, swallowing retraining device that combines sensory stimulation with motor retraining to rehabilitate swallow function, initially targeted for dysphagia patients. Dysphagia is a common disorder that creates difficulty swallowing. Patients at risk of choking on fluid or food face a risk of life-threatening aspiration pneumonia and may need to be fed through a tube.

Use of Therapeutic Antibodies as a Novel Treatment for Multiple Sclerosis

Multiple sclerosis (MS) is a disease of the central nervous system in which the immune system attacks the brain and spinal cord, typically resulting in muscle weakness, problems with vision and coordination, pain, and in some patients, cognitive impairments. The disorder affects approximately 400,000 people in the U.S. and more than 2.5 million people worldwide. Patients with relapsing forms of MS are currently treated with one of three FDA-approved interferon beta agents or with glatiramer acetate.