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Inventors at the NIH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) are seeking a licensee or collaborator for positive allosteric modulators (PAMs) of the A 3 adenosine receptor (A 3AR), a known therapeutic target. These heterocyclic chemical compounds bind to a lipid
The National Cancer Institute (NCI) is building a national resource of cancer cell models derived from patients in NCI-sponsored clinical trials. This Patient-Derived Models Repository (PDMR) will contain patient-derived xenografts, primary and metastatic tumor cell cultures, blood specimens, cancer
more than 2 million people worldwide, multiple sclerosis is a disease for which there is no cure. The disease starts when the immune system attacks myelin, a protective coating that forms around nerve cells in a person’s brain and spinal cord, to produce a variety of initial symptoms, including
The mission of NIMH is to translate the understanding and treatment of mental illnesses through basic and clinical research leading to prevention, recovery and cure. Many pharmaceutical companies generally prefer to invest in more profitable disease areas. NIMH Intramural Research Program (IRP)