NICHD | Technology Transfer

Enhanced Tumor Reactivity of T Cells Lacking SIT1, LAX1 or TRAT1

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Summary:

The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is actively seeking potential licensees interested in further developing these inhibitory transmembrane adapter proteins as targets for T-cell immunotherapy for the treatment of cancer, infectious diseases, and autoimmune diseases.

A Novel Transgenic Zebrafish Line Reporting Dynamic Epigenetic Changes

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Currently, there is no other whole-animal reporter for epigenetic regulation established in any vertebrate.

Cell Lines Expressing Nuclear and/or Mitochondrial RNAse H1

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The National Institute of Child Health & Human Development (NICHD), Program in Genomics of Differentiation, seeks interested parties to further co-develop small molecule inhibitors of RNase H1, especially in regards to genome instability, transcription, and translation.