NIH Patents and Patent Applications

This list includes non-provisional and PCT patent filings.

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Lead IC Reference Number Title Country Patent Application Type Application Number Date Filed Patent Number Date Issued Patent Status Patent PDF
NCI E-256-2020-0-PCT-04 IMIDAZO[1,2-A]PYRAZINE AND IMIDAZO[1,2-A]PYRIDINE BASED TYROSYL-DNA
PHOSPHODIESTERASE I (TDP1) INHIBITORS 		PCT PCT PCT/US2022/013946 Expired
NHLBI E-035-2022-0-US-01 PREPARATION OF ISOTOPICALLY LABELED KETOGLUTARATES AND METHODS OF HYPERPOLARIZATION THROUGH SIGNAL AMPLIFICATION BY REVERSIBLE EXCHANGE (SABRE) US 63/303,190 Expired
NCI E-266-2011-0-IL-60 T Cell Receptors Recognizing HLA-A1-or HLA-CW7- Restricted Mage IL DIV 2005-01-29 Issued
NIA E-024-2022-0-US-01 GINGERENONE A PRO-DRUGS AS SENOTHERAPEUTICS AND METHODS OF USE US 63/302,873 Expired
NIAID E-196-2022-0-PCT-02 Compositions And Methods For Treating Malaria PCT PCT PCT/US2022/013223 Expired
NCATS E-262-2016-0-HK-02 COMPOUNDS, COMPOSITIONS, METHODS FOR TREATING DISEASES, AND METHODS FOR PREPARING COMPOUNDS HK EP 42022046721.1 Abandoned
NCI E-135-2019-0-RU-12 T CELL RECEPTORS RECOGNIZING R175H OR Y220C MUTATION IN P53 RU National Stage 2022101295 Pending
NCI E-176-2014-0-HK-62 Anti-Human Papillomavirus 16 E7 T Cell Receptors HK CN 42022046605.6 Issued
NCI E-240-2015-1-MO-10 Methods of Analyzing Virus-Derived Therapeutics MO CN J/005746 Issued
NCI E-135-2019-0-IN-09 T CELL RECEPTORS RECOGNIZING R175H OR Y220C MUTATION IN P53 IN National Stage 202247003029 Pending
NHGRI E-104-2019-0-EP-03 SYNTHETIC GENES FOR THE TREATMENT OF PROPIONIC ACIDEMIA CAUSED BY MUTATIONS IN PROPIONYL-COA CARBOLXYLASE ALPHA EP National Stage 20743021.6 Pending
NIAID E-045-2015-0-HK-11 Neutralizing Antibodies to Ebola Virus Glycoprotein and Their Use HK EP 42022046399.6 Pending
NCI E-174-2018-2-AU-16 CAS9 Modified TILS For Treatment Of Gastrointestinal Cancer AU DIV 2022200267 Pending
NIAID E-055-2021-0-PCT-02 Replication-Competent Adenovirus Type 4-SARS-CoV-2 Vaccines And Their Use PCT PCT PCT/US2022/012530 Expired
NCI E-063-2017-0-US-08 DENOISING OF DYNAMIC RESONANCE SPECTROSCOPIC IMAGING USING LOW RANK APPROXIMATIONS IN THE KINETIC DOMAIN US CON 17/576,283 Pending
NIAID E-023-2022-1-US-01 NEUTRALIZING ANTIBODIES TO PLASMODIUM FALCIPARUM CIRCUMSPOROZOITE PROTEIN AND THEIR USE US 63/299,730 Expired
NCI E-045-2022-0-US-01 METHOD OF HLA LOH DETECTION IN LIQUID BIOPSIES US 63/299,672 Expired
NIDCD E-004-2019-1-HK-08 ADENO-ASSOCIATED VIRUSES AND THEIR USES FOR INNER EAR THERAPY HK EP 62022046132.6 Pending
NIDCD E-004-2019-0-HK-06 ADENO-ASSOCIATED VIRUSES AND THEIR USES FOR INNER EAR THERAPY HK EP 62022046131.8 Pending
NCI E-135-2019-0-ZA-14 T CELL RECEPTORS RECOGNIZING R175H OR Y220C MUTATION IN P53 ZA National Stage 2022/00598 Pending
NCATS E-244-2014-0-US-32 SMALL MOLECULE INHIBITORS OF LACTATE DEHYDROGENASE AND METHODS OF USE THEREOF US CON 17/572,359 11897845 Issued PDF
NCI E-051-2022-0-US-01 PREDICTING PATIENT TREATMENT RESPONSE AND RESISTANCE VIA SINGLE CELL TRANSCRIPTOMICS OF THEIR TUMORS US 63/298,045 Expired
NCATS E-057-2022-0-US-01 ESTRADIOL PRODRUGS AND METHODS OF USE THEREOF US 63/297,655 Expired
NIAID E-088-2022-0-US-01 Novel Immunogens For Influenza Virus Vaccines US 63/297,523 Expired
NIDCR E-129-2021-1-US-01 AQP1 Gene Therapy To Prevent Radiation Induced Salivary Hypofunction US 63/297,342 Expired
NCI E-014-2017-0-US-07 HUMAN MONOCLONAL ANTIBODIES SPECIFIC FOR FLT3 AND USES THEREOF US DIV 17/570,248 12012455 Issued PDF
NIBIB E-168-2021-1-US-01 Systems and Methods for Three-Dimensional Structured Illumination Microscopy With Isotropic Spatial Resolution Using Computational Means US 63/297,162 Expired
NHLBI E-144-2021-0-US-01 Tissue Cutting Systems and Methods US 63/297,226 Expired
NCI E-135-2019-0-AU-04 T CELL RECEPTORS RECOGNIZING R175H OR Y220C MUTATION IN P53 AU National Stage 2020308004 Pending
NIBIB E-237-2020-0-PCT-02 Producing Isotropic Super-Resolution Images From Line Scanning Confocal Microscopy PCT PCT PCT/US2022/011484 Expired
NIDDK E-051-2021-0-PCT-01 HETEROCYCLIC P2Y14 RECEPTOR ANTAGONISTS PCT PCT COMB PCT/US2022/011226 Expired
NCATS E-262-2016-0-US-06 COMPOUNDS, COMPOSITIONS, METHODS FOR TREATING DISEASES, AND METHODS FOR PREPARING COMPOUNDS US CON 17/568,023 Abandoned
NHGRI E-044-2013-1-JP-19 OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA JP DIV 2022-000125 Pending
NIAID E-132-2021-0-US-01_82723 Monoclonal Antibodies Specific for SARS-CoV-2 Spike Protein and Uses Thereof US 63/296,380 Expired
NCI E-046-2022-0-US-01 Neoantigen T Cell Therapy With Neoantigen Vaccination As A Combination Immunotherapy Against Cancer US 63/295,762 Expired
NIAID E-134-2020-1-PCT-01 Antibody-guided PCSK9 Immunogens Lacking 9-residue Sequence Overlap With Human Proteins PCT PCT COMB PCT/US2021/065856 Expired
NCI E-042-2014-0-JP-32 Chimeric Antigen Receptors Targeting CD-19 JP DIV 2021-215427 Issued
NHGRI E-034-2022-0-US-01 IMPROVED GENE THERAPY CONSTRUCTS FOR THE TREATMENT OF PROPIONIC ACIDEMIA CAUSED BY MUTATIONS IN PROPIONYL-COA CARBOXYLASE ALPHA US 63/294,511 Expired
NCI E-103-2019-0-US-07 MONOCLONAL ANTIBODIES THAT BIND EGFRVIII AND THEIR USE US National Stage 17/623,370 Pending
NHLBI E-186-2014-1-JP-16 SUPERAGONISTS, PARTIAL AGONISTS AND ANTAGONISTS OF INTERLEUKIN-2 JP DIV 2021-213818 Pending
NIDDK E-138-2017-0-IL-18 COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS IL DIV 289423 Pending
NCI E-135-2019-0-CN-07 T CELL RECEPTORS RECOGNIZING R175H OR Y220C MUTATION IN P53 CN National Stage 202080047882.0 Pending
NCI E-135-2019-0-JP-10 T CELL RECEPTORS RECOGNIZING R175H OR Y220C MUTATION IN P53 JP National Stage 2021-576970 Pending
NCI E-135-2019-0-BR-05 T CELL RECEPTORS RECOGNIZING R175H OR Y220C MUTATION IN P53 BR National Stage BR112021026408-6 Pending
NCI E-171-2020-0-PCT-02 EXO VII Inhibitor and Quinolone Antibiotic
Combination Useful for Treating Bacterial Infection 		PCT PCT PCT/US2021/064996 Expired
NCI E-022-2017-0-EP-05 METHODS FOR SELECTING THERAPY FOR A CANCER PATIENT EP DIV 21217161.5 Abandoned
NCATS E-022-2022-0-US-01 METHODS AND SYSTEMS FOR ANALYZING TARGET ENGAGEMENT DATA FROM BIOLOGICAL ASSAYS US 63/292,919 Expired
NIDDK E-085-2022-0-US-01 Next Generation Piggybac Transposasome US 63/292,821 Expired
NICHD E-210-2021-0-US-02 Kits And Methods For Predictions And Treatment Of Preeclampsia US CON 17/558,248 11782065 Issued PDF
NCI E-042-2014-0-US-31 CHIMERIC ANTIGEN RECEPTORS TARGETING CD-19 US CON 17/557,845 Pending