NIH Patents and Patent Applications

This list includes non-provisional and PCT patent filings.

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Lead IC Reference Number Title Country Patent Application Type Application Number Date Filed Patent Number Date Issued Patent Status Patent PDF
NIAID E-052-2023-0-PC-01 Combination therapy of N6 and Cabotegravir as a Therapeutic Treatment for HIV PCT PCT PCT/US2021/061697 Expired
NIAID E-120-2001-1-AU-06 Development of Mutations Useful for Attenuating Dengue Viruses and Chimeric Dengue Viruses AU DIV 2021282390 Expired
NCI E-175-2016-0-US-17 ANTI-KRAS-G12D T CELL RECEPTORS US CON 17/541,619 11840561 Issued PDF
NCI E-190-2014-0-US-44 VIRUS-LIKE PARTICLE CONJUGATES FOR DIAGNOSIS AND TREATMENT OF TUMORS US CON 17/540,549 Pending
NCI E-181-2018-2-HK-05 OXYNITIDINE DERIVATIVES USEFUL AS INHIBITORS OF TOPOISOMERASE IB (Top1) AND TYROSYL-DNA PHOSPHODIESTERASE 1(Tdp1) HK EP 62021043492.9 Pending
NCI E-040-2012-0-JP-66 Chimeric Antigen Receptors Targeting B-cell Maturation Antigen JP DIV 2021-196490 Pending
NCI E-239-2017-0-BR-19 HLA CLASS I-RESTRICTED T CELL RECEPTORS AGAINST MUTATED RAS BR DIV BR122021024382-4 Pending
NCI E-021-2015-0-AU-35 Anti-CD70 Chimeric Antigen Receptors AU DIV 2021277627 Issued
NCI E-040-2022-0-PC-01 METHODS FOR TREATING BILE DUCT CANCERS WITH TIVOZANIB PCT PCT PCT/US2021/060902 Pending
NEI E-089-2011-0-US-03 CONJUGATES FOR TREATING INFLAMMATORY DISEASE AND IDENTIFICATION OF PATIENTS LIKELY TO BENEFIT FROM SUCH TREATMENT US CON 17/534,909 Pending
NCI E-028-2015-1-US-42 ANTI-MUTATED KRAS T CELL RECEPTORS US CON 17/535,318 Pending
NCI E-080-2014-0-US-05 ZIRCONIUM-89 OXINE COMPLEX AS A CELL LABELING AGENT FOR
POSITRON EMISSION TOMOGRAPHY 		US DIV 17/532,083 Pending
NCI E-080-2014-0-US-06 ZIRCONIUM-89 OXINE COMPLEX AS A CELL LABELING AGENT FOR POSITRON EMISSION TOMOGRAPHY US CON 17/532,109 Pending
NIEHS E-241-2020-0-PCT-02 Massively Paralleled Multi-patient Assay For Pathogenic Infection Diagnosis And Host Physiology Surveillance Using Nucleic Acid Sequencing PCT PCT PCT/US21/59996 Expired
NICHD E-009-2021-0-PCT-02 THERAPEUTICS AGAINST PATHOGENIC CORONAVIRUSES PCT PCT PCT/US2021/060122 Expired
NCATS E-234-2020-0-PCT-02 Small Molecule Inhibitors of Sars-Cov-2 Infections PCT PCT PCT/US2021/059910 Expired
NEI E-162-2016-0-HK-33 GENE THERAPY FOR RETINITIS PIGMENTOSA HK EP 42021042687.0 Pending
NIAID E-021-2021-0-PCT-02 NOVEL VAR2CSA IMMUNOGENS AND METHODS OF USE THEREOF PCT PCT PCT/US2021/059941 Expired
NCATS E-010-2022-0-PCT-02 Protein And Lipid Therapeutic Targets PCT PCT PCT/US2021/059641 Expired
NCATS E-010-2022-0-US-02 Protein And Lipid Therapeutic Targets US National Stage 18/037,406 Pending
NCI E-109-2016-0-US-14 TARGETED CANCER THERAPY US DIV 17/528,827 Pending
NCI E-059-2013-0-HK-23 Methods of Producing Enriched Populations of Tumor-Reactive T Cells From Tumor HK EP 42021042576.5 Pending
NLM E-107-2010-2-US-35 SELECTIVE OXIDATION OF 5-METHYLCYTOSINE BY TET -FAMILY PROTEINS US CON 17/528,492 Abandoned
NCI E-202-2020-0-PCT-02 TYROSYL-LOCK PEPTIDES PCT PCT PCT/US2021/059764
NICHD E-209-2021-0-US-03 Kits And Methods To Distinguish False Labor And True Labor US DIV 17/525,717 11906528 Issued PDF
NICHD E-010-2021-0-PCT-02 ENHANCED ANTIGEN REACTIVITY OF IMMUNE CELLS EXPRESSING A MUTANT NON-SIGNALING CD3 ZETA CHAIN PCT PCT PCT/US2021/059109 Expired
NIAID E-064-2016-1-US-08 PREFUSION RSV F PROTEINS AND THEIR USE US CON 17/524,380 11878998 Issued PDF
NCATS E-098-2019-0-US-03 A SCALABLE SYNTHESIS OF DUAL-TARGET INHIBITOR OF CANNABINOID-1 RECEPTOR AND INDUCIBLE NITRIC OXIDE SYNTHASE US National Stage 17/610,537 Pending
NCI E-044-2021-0-PCT-02 SMALL MOLECULE INHIBITORS OF STAT3 N-TERMINAL DOMAIN AND METHODS OF USE PCT PCT PCT/US2021/058936 Expired
NHLBI E-197-2020-0-PCT-02 SINGLE-CELL PROFILING OF CHROMATIN OCCUPANCY AND RNA SEQUENCING PCT PCT PCT/US2021/058809 Expired
NIA E-249-2016-0-US-19 METHODS OF DELIVERING A NEUROPROTECTIVE POLYPEPTIDE TO THE CENTRAL NERVOUS SYSTEM US CON 17/522,687 11771657 Issued PDF
NHGRI E-034-2019-0-HK-16 NON-DISRUPTIVE GENE THERAPY FOR THE TREATMENT OF MMA HK EP 62021042143.9 Pending
NINR E-062-2022-0-PCT-03 Methods And Kits For Assessing Traumatic Brain Injury (TBI) Resulting From Blast Exposure PCT PCT PCT/US2021/072289 Expired
NIDDK E-011-2021-0-PCT-02 RNA SENSORS AND USES THEREOF PCT PCT PCT/IL2021/051318 Expired
NIDDK E-011-2021-0-US-02 RNA SENSORS AND USES THEREOF US National Stage 18/252,086 Pending
NINR E-062-2022-0-EP-01 Methods And Kits For Assessing Traumatic Brain Injury (TBI) Resulting From Blast Exposure EP National Stage 21815867.3 Pending
NINR E-062-2022-0-US-02 Methods And Kits For Assessing Traumatic Brain Injury (TBI) Resulting From Blast Exposure US ORD 17/453,991 Pending
NIAID E-251-2020-0-US-02 PPMO Targeting SARS-CoV-2 Genomic RNA To Treat And Prevent Coronavirus Infection US CIP 18/053,308 Pending
NCI E-231-2020-0-PC-01 RBD-ligand Utilization To Distinguish CAR-T Cells With Increased Anti-leukemia Effector Function PCT PCT PCT/EP2021/080796 Expired
NIAID E-060-2015-0-US-17 NOVEL MULTIVALENT NANOPARTICLE-BASED VACCINES US DIV 17/519,142 11938221 Issued PDF
NIAID E-064-2016-1-AU-09 SUBSTITUTIONS-MODIFIED PREFUSION RSV F PROTEINS AND THEIR USE AU DIV 2021261932 Issued
NCI E-060-2021-0-PCT-02 ANTIVIRAL STRUCTURALLY-STABILIZED EBOLAVIRUS PEPTIDES AND USES THEREOF PCT PCT PCT/US2021/058023 Expired
NCI E-064-2019-0-US-04 CHIMERIC ANTIGEN RECEPTORS TARGETING GLYPICAN-2 US National Stage 17/608,832 Pending
NCI E-060-2021-0-EP-01 ANTIVIRAL STRUCTURALLY-STABILIZED EBOLAVIRUS PEPTIDES AND USES THEREOF EP National Stage 21820745.4 Pending
NHLBI E-005-2021-0-PCT-02 MODIFIED NK CELLS WITH REDUCED CCR5 EXPRESSION AND METHODS OF THEIR USE PCT PCT PCT/US2021/057845 Expired
NHLBI E-085-2019-0-CN-02 METHODS FOR ASSESSING CARDIOVASCULAR DISEASE OR INFLAMMATORY DISEASE RISK USING NON-EXCHANGEABLE LIPID PROBE CN National Stage 202080033275.9 Pending
NIAID E-081-2013-4-RU-20 Prefusion RSV F Proteins And Their Use RU DIV 2021132097 Pending
NIAID E-106-2016-0-US-05 PEPTIDE VACCINE FORMULATIONS AND USE THEREOF FOR INDUCING AN IMMUNE RESPONSE US CON 17/517,597 11938177 Issued PDF
NIAID E-087-2019-0-US-03 NEUTRALIZING ANTIBODIES TO PLASMODIUM FALCIPARUM CIRCUMSPOROZOITE PROTEIN AND THEIR USE US National Stage 17/608,381 Pending
NCI E-150-2020-0-PCT-02 Synthetic Lethality-Mediated Precision Oncology via the Tumor Transcriptome PCT PCT PCT/US2021/057229 Expired