Product Showcase

The HHS Intramural Research Programs have invented numerous technologies that were licensed to companies for commercial development and now are on the market. Products showcased on this site are utilized every day to detect, treat or prevent disease or assist researchers as they continue to explore ways to develop newer and more effective health care products and procedures.

The Showcase includes products that are now or have been on the market. Some are FDA-approved and many do not necessitate FDA approval. While there may be multiple inventors on any product, all of whom may not be from HHS, the primary purpose of this Showcase is to highlight the contributions of HHS. 

We hope you will find this Showcase illuminating about the role the HHS Intramural Research Programs have played in the effort to advance significantly our capacity to protect and improve health.

Upstate Biotechnology, Incorporated

Identify PLK enzymes in vitro

Becton, Dickinson and Company

Selectively and potently inhibits the human cytochrome p450

PeproTech, Inc.

Circulating human IL-8 might be a useful, clinically relevant circulating tumor protein marker due to its positive correlation with multiple physiologic variables associated with lung cancer progression

Dako Denmark A/S

Reacts with and labels cells expressing p24

Upstate Biotechnology, Incorporated

Identify and trace specific cells or molecules in an organism

Oncogene Sciences, Inc.

Used to detect NM23 in human tumors to predict the malignancy potential of such tumors

BD Biosciences - BD PharMingen

Expression of the protein correlates with metastatic potential of tumors

Trevigen, Inc.

Research tool for studying human p53 protein functions

Oncotech Incorporated

Specifically reacts to human thymidylate synthase

QED Bioscience, Inc.

Used for de novo synthesis of DNA and reacts specifically with human Thymidylate Synthase

Bayer Corporation

In vivo or in vitro use for detecting or treating human cancer

Becton, Dickinson and Company

Applications in research, diagnostics, and treatment due to its effects on cell attachment, spreading, and migration

Becton, Dickinson and Company

Applications in research, diagnostics, and treatment due to its effects on cell attachment, spreading, and migration

Research and Diagnostic Systems, Inc.

Detection of individual cells secreting specific cytokines

Charles River Laboratories

Provides a method of inducing tolerance in a recipient mammal of a first species to a graft from a donor mammal of a second species

Innogenetics, N.V.

Diagnostic test that can differentiate between HIV-1 and HIV-2

Santa Cruz Biotechnology, Inc.

Used for the detection of IL-2 of human origin

Ancell Corporation

Antibodies against CD25 for potential use as an immunodirected therapy to selectively attack (kill) CD25 expressing cells

BD Biosciences - BD PharMingen

Antibody reacts with the 72 and 77 amino acid forms of human IL-8

Beckman Coulter, Inc.

iTAg reagents allow for measurement against one specific peptide

Beckman Coulter, Inc.

Used for the ex vivo quantification of cellular immune response

Zymed Laboratories, Inc.

Used as a research reagent to enhance the understanding of certain cancers, such as, ovarian, esophageal and cervical carcinomas

Amgen, Inc.

Treatment of severe mouth sores that afflict hematologic cancer patients who receive myelotoxic therapy

PeproTech, Inc.

Identifies keratinocyte of growth factors, i.e. embryonic development, cell growth, morphogenesis, tumor growth,and invasion

Stratagene California

Detect in vivo mutations of E. coli phage lambda 1

Stratagene California

Uses LTR vectors to screen for a protein of interest.

Novartis Pharma, Genetic Therapy, Inc.

Used to make retroviral vectors for development of gene therapy products

GlaxoSmithKline

A noninfectious recombinant vaccine for Lyme's disease

Research and Diagnostic Systems, Inc.

Activates macrophages to react in the immune system

Cell Marque Corporation

Diagnostic assay for metastatic melanoma