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NIH inventors have developed an image-based machine learning system that is able to validate functional cell phenotypes. The system may be trained to automatically recognize image features that correlate with a desired cell-type or properties for research, diagnostic, and therapeutic purposes. This
NIH inventors are seeking a licensee or collaborator for a micro-engineered “thyroid-on-a-chip” that combines human thyroid organoids with integrated micro-vasculature to replicate the gland’s native blood flow and 3-D architecture, enabling rapid, patient-specific drug screening. This technology
Inventors at the NIH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) are seeking a licensee or collaborator for positive allosteric modulators (PAMs) of the A 3 adenosine receptor (A 3AR), a known therapeutic target. These heterocyclic chemical compounds bind to a lipid
The “Top 10” list of best-selling gene therapies published by Genetic Engineering & Biotechnology News (GEN) in their May 2025 issue features three products based upon license agreements for technologies originating from the NIH Intramural Research Program. Featured and ranked on the GEN list are