Current cold storage solutions or methods for cells, tissues, and organs are suboptimal due to irreversible damage to cold-sensitive tissue or organ transplants that need long term storage for facilitating clinical practices. NIH inventors have developed an invention to preserve the viability of

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Conventional cryopreservation of three-dimensional tissue constructs can have several problems: They can suffer damage from tensional stresses experienced during expansion and contractions that occur during freezing and thawing. Uneven physical changes within the tissue during cooling or warming can