Precision, Optimally Targeted, ElectroConvulsive Therapy (PROTECT)
The PRecision, Optimally Targeted Electroconvulsive Therapy (PROTECT) is a novel stimulator device, which aims to improve the treatment of treatment-resistant depression (TRD). Millions of individuals suffer from TRD for which electroconvulsive therapy (ECT) is often the most efficacious treatment option; yet present devices lack precision in electric field delivery, leading to variable outcomes and cognitive side effects. PROTECT is a next-generation stimulator designed to revolutionize ECT through its novel waveforms and pulse patterns, which optimize brain stimulation with unparalleled precision. By integrating cutting-edge computational modeling and advanced hardware, PROTECT enables customized stimulation paradigms, enhancing efficacy while reducing unwanted side effects. This technology sets a new standard for ECT, offering clinicians and patients a more targeted, effective, and personalized approach to treatment.
- Treatment Resistant Depression (TRD)
- Major Depressive Episode associated with major depressive disorder (MDD) or bipolar disorder (BP)
- Catatonia
- Schizophrenia
- Schizoaffective disorder
- Schizophreniform disorder
- Status epilepticus
- offer both conventional AND complex stimulation patterns along with advanced computational modeling
- be complemented with state-of-the-art computational E-field modeling and optimization algorithms that can used to achieve optimized dosimetry for seizure therapy
- allow individualized dosing to maximize therapeutic effect, while reducing side effects of convention ECT