Technology ID
TAB-4603

Paper Strip Tool with Gold Nanoparticle Conjugated Probes for Rapid Detection of Pathogens in Stool

E-Numbers
E-134-2015-0
Lead Inventor
Henderson, Wendy
Co-Inventors
Kim, Chang Hee (GoDx, Inc)
Fourie, Nicolaas
Ferguson, Eric
Abey, Sarah (NINR)
Applications
Research Materials
Diagnostics
Development Stages
Pre-clinical (in vivo)
Research Products
Research Equipment
Lead IC
NINR
ICs
NINR

This technology includes a paper strip tool that may be used at the point-of care to detect the presence of a multiplex of pathogen nucleic acid sequences in stool without the need for molecular amplification, laboratory or instrumentation. This invention can be used to rapidly and inexpensively detect gastrointestinal and diarrheal disease in order to guide treatment.

Commercial Applications
Diagnostic for pathogens that cause diarrheal disease which kills over 1 million children worldwide annually; likewise, may be useful for hospital-based screening of pathogens.

Competitive Advantages
The invention is rapid, inexpensive, does not require enzymes or refrigeration, does not require PCR or a laboratory, does not require a scanner, and can detect a multiplex of pathogens in stool.

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Licensing Contact:
Kolesnitchenko, Vincent
vk5q@nih.gov

Patents

  • US
    Provisional (PRV) 62/162,668
    Filed on 2015-05-16
    Status: Abandoned
  • Patent Cooperation Treaty
    (PCT) PCT/US16/032788
    Filed on 2016-05-16
    Status: Expired
  • US
    National Stage 15/574,750
    Filed on 2017-11-16
    Status: Abandoned
  • US
    Divisional (DIV) 16/941,333
    Filed on 2020-07-28
    Status: Pending
Date Published