Technology ID
TAB-4601

Cytochrome P450 CYP2J Polyclonal Antibodies and Recombinant Proteins for Immunoblotting and Metabolism Studies

E-Numbers
E-153-2011-1
Lead Inventor
Graves, Joan (NIEHS)
Co-Inventors
Zeldin, Darryl (NIEHS)
Goldstein, Joyce (NIEHS)
Bradbury, Jennifer (NIEHS)
Blaisdell, Joyce (NIEHS)
Applications
Research Materials
Therapeutic Areas
Metabolic Disease
Development Stages
Pre-Clinical (in vitro)
Research Products
Plasmids/Vectors
Antibodies
Lead IC
NIEHS
ICs
NIEHS

This technology includes identified members of the mouse cytochromes P450 CYP2J subfamily and antibodies to them for P450 expression studies and metabolism research. Recombinant proteins of the CYP2J subfamily members have also been expressed. The CYP2J subfamily members have a wide tissue distribution and may be useful as model systems for studies of cardiovascular disease, drug metabolism, and toxicity.

Commercial Applications
The various antibodies for CYP2Js will enable studies on the expression of these P450s in various tissues by immunohistochemistry and immunoblotting. The recombinant proteins can be used as controls in immunoblotting as well as for metabolism studies.

Competitive Advantages
Wide potential for utilization.

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Licensing Contact:
Choudhry, Vidita
vidita.choudhry@nih.gov
Date Published