Technology ID
TAB-4501

Monoclonal Antibody Against Human Zinc Finger RNA-binding Protein (ZFR)

E-Numbers
E-121-2018-0
Lead Inventor
Hogg, John (NHLBI)
Co-Inventors
Haque, Nazmul (NHLBI)
Applications
Research Materials
Development Stages
Pre-Clinical (in vitro)
Research Products
Antibodies
Lead IC
NHLBI
ICs
NHLBI

This technology includes monoclonal antibody was raised in mice against amino acids 703-1074 of ZFR. Antibody specificity was confirmed by immunoblotting lysates from cells depleted of ZFR using shRNAs.

Commercial Applications
Potential for use in research and clinical diagnosis and treatments.

Competitive Advantages
The monoclonal antibody generated allows more robust and specific immunoblotting than the other commercially available ZFR antibodies, and because it was raised against the C-terminus of the protein, it detects alternative ZFR isoforms found to be regulated in a cell-type specific manner.

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Licensing Contact:
Shmilovich, Michael
shmilovm@nih.gov

Publications

Collaborations

  • Materials Available

Collaboration Description

  • We are seeking statements of capability or interest from parties interested in collaborative research to further developer, evaluate, or commercialize this technology.
Date Published