Technology ID
TAB-4485
Device for Closure of Transvascular or Transcameral Access Ports
E-Numbers
E-068-2014-0
Lead Inventor
Lederman, Robert (NHLBI)
Co-Inventors
Kocaturk, Ozgur (NHLBI)
Rogers, Toby (Med Star Washington Hospital Center)
Ratnayaka, Kanishka (Rady Children's Hospital, San Diego)
Rafiee, Nasser (Mehr Medical)
Applications
Research Materials
Medical Devices
Therapeutic Areas
Cardiology
Development Stages
Pre-clinical (in vivo)
Research Products
Research Equipment
Lead IC
NHLBI
ICs
NHLBI
This technology includes part of transcatheter aortic valve replacement and to enable non-surgical thoracic aortic aneurysm endograft repair. The invention enables a completely new way to access the arterial circulation to allow introduction of large devices, such as transcatheter aortic valve replacement, percutaneous left ventricular assist devices, and thoracic aortic endografts. It also can be used in most labeled and off-label applications of Amplatzer (AGA Medical, St Jude) nitinol occluder devices to occlude intracardiac holes and to allow non-surgical direct access to the heart. This invention has been applied, using marketed devices off-label, in 15 patients.
Commercial Applications
Permanent medical implant for use as part of transcatheter aortic valve replacement and to enable non-surgical thoracic aortic aneurysm endograft repair.
Competitive Advantages
The unique features of the device which are not available in commercial devices marketed for the occlusion of congenital heart and vascular defects include:
- Multiple disks, especially the favored three-disc embodiment with intra-aortic, extra-aortic, and venous disks
- Billowed nitinol disk, especially in the preferred embodiment of the extra-aortic disk, occupies space to achieve hemostasis on the aortic rent
- Tether mechanism for independent control of multiple disks during deployment
Licensing Contact: