Technology ID
TAB-4259

Software for Modeling Delivery and Penetration of Antibody Conjugates

E-Numbers
E-060-2012-0
Lead Inventor
Lee, Byungkook (NCI)
Co-Inventors
Pak, Youngshang (Pusan National University)
Pastan, Ira (NCI)
Applications
Software / Apps
Therapeutic Areas
Oncology
Development Stages
Prototype
Lead IC
NCI
ICs
NCI

The National Cancer Institute (NCI) seeks parties to license software for modeling the targeted delivery of anti-cancer agents in solid tumors.

The software models the permeability and concentration of intravenously administered antibody anti-cancer agent conjugates in solid tumors.  The models can be used to determine optimal dosing regimen of a therapeutic in a particular cancer type.  Thirty factors that affect delivery rates and efficiencies are analyzed as variables in generating the models.

Competitive Advantages:

  • Accurate permeability modeling of anti-cancer therapeutics.

Commercial Applications:

  • Drug design
  • Combination therapy
  • Personalized medicine
Licensing Contact:
Lambertson, David
david.lambertson@nih.gov