Technology ID
TAB-393

Method Of Identifying Inhibitors Of The Jak-STAT Signal Transduction Pathway

E-Numbers
E-176-1995-0
Co-Inventors
Leonard, Warren
Applications
Therapeutics
Research Materials
Diagnostics
Lead IC
NHLBI
The invention provides identification methods for agents which inhibit the Jak-STAT signaling transduction pathway. Drugs identified by these methods are candidates for the treatment of proliferative disorders dependent on the Jak-STAT pathway, including those caused by HTLV-1. In addition, such agents may be potent immunosuppressive drugs with potential applications not only for organ transplantation but also for treatment of autoimmune diseases.

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Licensing Contact:
Shmilovich, Michael
shmilovm@nih.gov

Patents

  • US Patent 6,265,160
    Filed on 1998-01-07
    Status: Abandoned
  • US
    Provisional (PRV) 60/000,971
    Filed on 1995-07-07
    Status: Abandoned
  • Patent Cooperation Treaty
    (PCT) PCT/US1996/011206
    Filed on 1996-07-02
    Status: Abandoned

Collaborations

  • Licensing
Date Published