Technology ID
TAB-3742
Polyclonal Antibodies to Apolipoprotein L1 for Use in Basic Science Research
E-Numbers
E-099-2012-0
Lead Inventor
Kopp, Jeffrey (NIDDK)
Co-Inventors
Dummer, Patrick (NIDDK)
Pisitkun, Trairak (NHLBI)
Applications
Research Materials
Therapeutic Areas
Ophthalmology
Oncology
Infectious Disease
Immunology
Endocrinology
Dental
Cardiology
Research Products
Antibodies
Lead IC
NIDDK
ICs
NIDDK
NHLBI
This technology includes antibodies to apolipoprotein L1 (ApoL 1) to be used in basic science laboratory studies. ApoL 1 is a protein that is present within cells and circulates as component of high-density lipoprotein. Its functions are not well understood. Recently APOL 1 genetic variants have been shown to be highly associated with kidney disease in African Americans.
Commercial Applications
Utilization in basic science laboratory work: Immunostaining of cells or tissue, Western blotting, immunoprecipitation, possibly a capture ELISA.
Competitive Advantages
- K5 antibody: peptide in N terminal portion is unique in that there are no commercially available ApoL 1 N terminal antibodies with an epitope that does not overlap the signaling peptide.
- K9 antibody: peptide in C terminal portion is peptide selected is unique in that it that does not overlap the ApoL 1 kidney-disease risk mutations.
Licensing Contact: