Technology ID
TAB-3546
New Antimalarial Chemotypes Discovered Through Chemical Methodology and Library Development
E-Numbers
E-221-2011-0
Lead Inventor
Synder, John
Lead IC
NCATS
Co-Inventors
Inglese, James
Cheng, Chih-Chien (Ken)
Macarthur, Ryan
Guha, Rajarshi
Su, Xin-zhuan
Yuan, Jing
Ni, Feng
Beeler, Aaron
Schaus, Scott
Brown, Lauren
Porco, John
ICs
NIAID
NCATS
Applications
Therapeutics
Therapeutic Areas
Infectious Disease
This technology includes three new compound classes displaying either differential or comprehensive antimalarial activity across geographically diverse lines. These compounds were identified from a quantitative high throughput screen of a novel chemical library with unique chemical complexity and are potential candidates for treating malaria.
Commercial Applications
This new compound class will be utilized to treat malaria.
Competitive Advantages
Compounds display comprehensive antimalarial activity.
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