Technology ID
TAB-3085

Immortalized Stria Vascularis Cell Line SV-k1

E-Numbers
E-013-2017-0
Lead Inventor
Canseco De Kalinec, Gilda
Co-Inventors
Kalinec, Federico (University of California, Los Angeles (UCLA))
Applications
Research Materials
Therapeutic Areas
Ophthalmology
Oncology
Infectious Disease
Endocrinology
Dental
Cardiology
Lead IC
NIDCD

Available for nonexclusive licensing for research uses is the cell line, SV-k1, derived from the Organ of Corti. The line was developed from the stria vascularis, an organ localized on the lateral wall of the cochlea, adjacent to the Organ of Corti, containing cell populations specialized in the production of an endolymph very rich in K+ characteristic of the mammalian inner ear. SV-k1 cells express a set of biomarkers completely different of those expressed by OC-k3 cells, and are not sensitive to ototoxic drugs.

Commercial Applications
  • Research
  • Hearing research
Licensing Contact:
Shmilovich, Michael
shmilovm@nih.gov