Technology ID
TAB-2938

Monoclonal Antibodies to the HIV-1 Core Protein p24

E-Numbers
E-150-2014-0
Lead Inventor
Granade, Timothy (CDC)
Co-Inventors
Pau, Chou-Pong (CDC)
Nguyen, Shon (CDC)
Wells, Susan (CDC)
Owen, Sherry (CDC)
Goldstein, Jason (CDC)
Bagarozzi, Dennis (CDC)
Applications
Research Materials
Diagnostics
Therapeutic Areas
Infectious Disease
Immunology
Development Stages
Pre-Clinical (in vitro)
Development Status
  • In vitro data available
  • Prototype
Research Products
Research Equipment
Antibodies
Lead IC
CDC
ICs
CDC
The core proteins of HIV-1 are secreted into the environment during replication in the human body. The detection of the core protein p24 (molecular mass of 24 kilodaltons) serves as an indicator of early HIV-1 infection, and assays detecting it have been available since the late 1980s. However, the development of a rapid assay for the detection of HIV-1 p24 has only recently become available. Monoclonal antibodies developed in our laboratory for research and development of a rapid HIV-1 p24 assay would provide large quantities of material at a much lower price than could be obtained in the commercial market.
Commercial Applications
  • Diagnostic assay for the detection of HIV-1
  • Research tool used to study HIV-1
Competitive Advantages
  • Inexpensive antibodies to HIV-1 core proteins
  • Larger source of HIV-1 monoclonal antibodies

Request More Info

Licensing Contact:
Mitzelfelt, Jeremiah
jeremiah.mitzelfelt@nih.gov

Publications

Collaborations

  • Licensing
Date Published