Technology ID
TAB-2604
Rabbit Antibody to Mouse Sphingosine-1-phosphate (S1P) lyase
E-Numbers
E-465-2013-0
Lead Inventor
Proia, Richard (NIDDK)
Applications
Therapeutics
Research Materials
Diagnostics
Development Status
In vitro data available
Lead IC
NIDDK
ICs
NIDDK
The cleavage of sphingoid base phosphates by sphingosine-1-phosphate (S1P) lyase to produce phosphoethanolamine and a fatty aldehyde is the final degradative step in the sphingolipid metabolic pathway. Researchers at NIH injected rabbits with the C-terminal peptide of the mouse S1P lyase — 551-TTDPVTQGNQMNGSPKPR-568 — to develop an antibody that can be used in western blotting to study this pathway.
Commercial Applications
The antibody can be used to detect and measure S1P lyase.
Competitive Advantages
The antibody works very well for western blotting.
Licensing Contact: