Technology ID
TAB-4495

A Method to Guide Protocol Development for Magnetic Resonance Thermometry

E-Numbers
E-111-2019-0
Lead Inventor
Campbell-Washburn, Adrienne (NHLBI)
Co-Inventors
Majeed, Waqas (Siemens Medical Solutions USA Inc)
Schneider, Rainer (Siemens Healthineers AG)
Bhat, Himanshu (Siemens Medical Solutions USA, Inc)
Applications
Medical Devices
Development Stages
Pre-clinical (in vivo)
Research Products
Research Equipment
Computational models/software
Lead IC
NHLBI
ICs
NHLBI

This technology includes tools to guide optimization of thermometry imaging/post-processing protocols. Proton Resonance Frequency (PRF) thermometry is a widely used Magnetic Resonance Imaging (MRI) based technique to monitor changes in tissue temperature in response to thermal therapy. The use of PRF thermometry with thermal therapy procedures is indispensable to ensure delivery of desired thermal dose to the target tissue, and to minimize unintended damage to the normal tissue.

Commercial Applications
PRF thermometry is a high impact application of MRI and plays a critical role in guiding thermal therapy procedures. Our approach solves a significant problem encountered in routine clinical application of PRF thermometry and can therefore be of significant commercial value.

Competitive Advantages
  • The invention is based on well-established principles of MR physics and statistics, and therefore results in reliable predictions
  • No competing solutions present in the literature
  • Given the immense utility of the features proposed in this invention, this will become a must-have feature on commercial MR Thermometry related products
Licensing Contact:
Mistry, Pragnesh
pragnesh.mistry@nih.gov