Technology ID
TAB-3266
Potential New Drugs for Treating or Preventing Pruritus
E-Numbers
E-485-2013-1
E-485-2013-2
Lead Inventor
Hoon, Mark (NIDCR)
Co-Inventors
Solinski, Hans (NIDCR)
Inglese, James (NCATS)
Dranchak, Patricia (NCATS)
Applications
Vaccines
Therapeutics
Consumer Products
Therapeutic Areas
Reproductive Health
Ophthalmology
Oncology
Infectious Disease
Endocrinology
Dental
Cardiology
Development Stages
Discovery
Research Products
Research Equipment
Lead IC
NIDCR
ICs
NIDCR
NCATS
NIH scientists have identified new compositions that could potentially be used to treat or prevent pruritus (itchiness). The newly discovered compounds can block a newly identified itch pathway and might be effective for persistent itch caused by psoriasis, atopic dermatitis, renal failure, liver cirrhosis and chemotherapy. These compounds are different from commonly used antihistamines which induce drowsiness and sedation. These compounds have the potential to be used for human and animals.
Commercial Applications
- Therapeutics for preventing or treating pruritus/itching.
Competitive Advantages
- A new category of drug for pruritus treatment.
- Various screening tests used to minimize potential side effects.
Licensing Contact: