Fluorescence Scanning System for Improvement of Analytical Ultracentrifugation

This technology includes improvements in the fluorescence scanner to increase efficiency. This method works by eliminating the need to radially slide the optical assembly during scanning, instead using a galvanometric mirror deflecting a laser beam to different positions in the sample. This allows the scanner to be incorporated into existing commercial analytical ultracentrifugation (AUC) systems with minimal modifications.

Computer-Aided Diagnostic for Use in Multiparametric MRI for Prostate Cancer

Multiparametric MRI improves image detail and prostate cancer detection rates compared to standard MRI. Computer aided diagnostics (CAD) used in combination with multiparametric MRI images may further improve prostate cancer detection and visualization. The technology, developed by researchers at the National Institutes of Health Clinical Center (NIHCC), is an automated CAD system for use in processing and visualizing prostate lesions on multiparametric MRI images.

Zirconium-89 PET Imaging Agent for Cancer

Researchers at the NCI Radiation Oncology Branch  and NIH CIT Center for Molecular Modeling developed a tetrahydroxamate chelation technology that provides a more-stable Zr-89 complex as an immuno-PET cancer imaging agent. In either the linear or the macrocyclic form, the tetrahydroxamate complexes exhibit greater stability as chelating agents compared to Zr-89 complexed to the siderophore desferrioxamine B (DFB), a trihydroxamate, which represent

Video Monitoring and Analysis System for Vivarium Cage Racks

This invention pertains to a system for continuous observation of rodents in home-cage environments with the specific aim to facilitate the quantification of activity levels and behavioral patterns for mice housed in a commercial ventilated cage rack.  The home-cage in-rack provides daytime and nighttime monitoring with the stability and consistency of a home cage environment.