FY-2008 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
Rank   
2HPV Vaccines Based Upon Recombinant Papillomavirus Capsid ProteinsLowy et al.NCI
3Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
4Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1Erickson et al.NCI
5Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
7AIDS Drug ddIMitsuya et al.NCI
8Synthetic Thyrotropin as Adjuvant in Thyroid CancerWondisford et al.NIDDK
10Paclitaxel as a Cancer TreatmentWilson et al.NCI
11Nutritional Supplement to Treat Macular DegenerationFerris et al.NEI
12Hepatitis A Vaccine (Strain HM-175)Daemer et al. / Funkhouser et al.NIAID
14Vaccinia Virus Vector Used in Veterinary Biologicals/VaccinesMoss et al.NIAID
17Palifermin for Treatment of Oral MucositisRubin et al.NCI
 
 
photo: human puzzle with stethoscopeDIAGNOSTICS
Rank   
6Serological Detection of Antibodies to HIV-1Gallo et al. / Montagnier et al.NCI
9DNA Probe for Breast Cancer DiagnosisKing et al.NCI
15Norwalk Virus - IVD ProductGreen et al.NIAID
18Genoyping of HIV Protease GeneOroszlan et al.NCI
20Serological Detection of Antibodies to HTLV-1Papas et al.NCI
 
 
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
Rank   
1Paclitaxel-Eluting Coronary Stent SystemKinsella et al.NIA
13Diffusion Tensor Magnetic Resonance ImagingBasser et al.NICHD
16Enhanced Magnetic Resonance Imaging Through Magnetization TransferBalaban et al.NHLBI
 
 
photo: laboratory glasswareRESEARCH MATERIALS
Rank   
19Purified Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI