FY-2006 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
Rank   
2Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
3AIDS Drug ddIMitsuya et al.NCI
4Synthetic Thyrotropin as Adjuvant in Thyroid CancerWondisford et al.NIDDK
6Paclitaxel as a Cancer TreatmentWilson et al.NCI
7Hepatitis A Vaccine (Strain HM-175)Daemer et al. / Funkhouser et al.NIAID
8Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
9Nutritional Supplement to Treat Macular DegenerationFerris et al.NEI
10Radioimmunotherapy for Non-Hodgkin's LymphomaGansow et al.NCI
15Palifermin for Treatment of Oral MucositisRubin et al.NCI
16Cyclodextrin Formulations for Treatment of ThrushPithaNIA
 
 
photo: human puzzle with stethoscopeDIAGNOSTICS
Rank   
5Serological Detection of Antibodies to HIV-1Gallo et al. / Montagnier et al.NCI
11DNA Probe for Breast Cancer DiagnosisKing et al.NCI
13Genoyping of HIV Protease GeneOroszlan et al.NCI
17Serological Detection of Antibodies to HTLV-1Papas et al.NCI
20Parvovirus Capsids for Detection of B19 Virus AntibodiesYoung et al.NHLBI
 
 
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
Rank   
1Paclitaxel-Eluting Coronary Stent SystemKinsella et al.NIA
12Enhanced Magnetic Resonance Imaging Through Magnetization TransferBalaban et al.NHLBI
 
 
photo: laboratory glasswareRESEARCH MATERIALS
Rank   
14Neutrophil Chemotactic Factor (IL-8)Matsushima et al.NCI
18Reconstituted Basement MembraneKleinman et al.NIDCR
19Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI