Technology ID
TAB-3015
Murine Cell Models for Metastatic Squamous Cell Carcinoma
E-Numbers
E-213-2016-0
Lead Inventor
Chen, Zhong
Lead IC
NIDCD
Co-Inventors
Van Waes, Carter
ICs
NIDCD
Applications
Research Materials
Therapeutic Areas
Oncology
Two cell lines isolated from Pam 212 cells (SCC): Pam LY (lymph node metastasis) and Pam LU (lung metastasis) from metastated in vivo growth in mouse. These stably established cell lines exhibited higher potential to metastasize to lymph nodes and lungs, respectively, in mouse models than their parental Pam 212 cells.
Commercial Applications
- Drug discovery for squamous cell carcinoma
- Drug discovery for squamous cell carcinoma metastated to lung and lymph nodes
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