Cell Lines for the Study of Neurodegenerative Disorders and their Treatments Available for Licensing

Gaucher disease is a rare and heterogenous disorder caused by inherited Glucocerebrosidase (GBA1) genetic mutations. The National Human Genome Research Institute (NHGRI) has six cell lines available for licensing for the study of GBA1 mutations. These cell lines can be used to study the defects in the GBA1 gene and protein and to screen small molecules for involvement in Gaucher disease and other neurodegenerative diseases involving GBA1. There appears to be a link between GBA1 mutations, Gaucher’s disease and Parkinson’s disease.

These cell lines could be used for the evaluation and eventual treatments for Gaucher’s disease, Parkinson’s disease, and other neurodegenerative disorders. If you are interested in learning more about this available technology or speaking with the licensing contact, please view the abstract here.