FY-2006 Top 20 Commercially Successful Inventions
(based on royalties on product sales)
VACCINES & THERAPEUTICS | |||
Rank | |||
2 | Monoclonal Antibody for Treatment of RSV | Murphy et al. | NIAID |
3 | AIDS Drug ddI | Mitsuya et al. | NCI |
4 | Synthetic Thyrotropin as Adjuvant in Thyroid Cancer | Wondisford et al. | NIDDK |
6 | Paclitaxel as a Cancer Treatment | Wilson et al. | NCI |
7 | Hepatitis A Vaccine (Strain HM-175) | Daemer et al. / Funkhouser et al. | NIAID |
8 | Proteosome Inhibitor for Treatment of Multiple Myeloma | Gupta et al. | NCI |
9 | Nutritional Supplement to Treat Macular Degeneration | Ferris et al. | NEI |
10 | Radioimmunotherapy for Non-Hodgkin's Lymphoma | Gansow et al. | NCI |
15 | Palifermin for Treatment of Oral Mucositis | Rubin et al. | NCI |
16 | Cyclodextrin Formulations for Treatment of Thrush | Pitha | NIA |
DIAGNOSTICS | |||
Rank | |||
5 | Serological Detection of Antibodies to HIV-1 | Gallo et al. / Montagnier et al. | NCI |
11 | DNA Probe for Breast Cancer Diagnosis | King et al. | NCI |
13 | Genoyping of HIV Protease Gene | Oroszlan et al. | NCI |
17 | Serological Detection of Antibodies to HTLV-1 | Papas et al. | NCI |
20 | Parvovirus Capsids for Detection of B19 Virus Antibodies | Young et al. | NHLBI |
INSTRUMENTATION & DEVICES | |||
Rank | |||
1 | Paclitaxel-Eluting Coronary Stent System | Kinsella et al. | NIA |
12 | Enhanced Magnetic Resonance Imaging Through Magnetization Transfer | Balaban et al. | NHLBI |
RESEARCH MATERIALS | |||
Rank | |||
14 | Neutrophil Chemotactic Factor (IL-8) | Matsushima et al. | NCI |
18 | Reconstituted Basement Membrane | Kleinman et al. | NIDCR |
19 | Transforming Growth Factor Beta (TGF-beta) | Sporn et al. | NCI |