FY-2011 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
Rank   
1Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1Erickson et al.NCI
2HPV Vaccines Based Upon Recombinant Papillomavirus Capsid ProteinsLowy et al.NCI
3Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
4Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
6Nutritional Supplement to Treat Macular DegenerationFerris et al.NEI
9Paclitaxel as a Cancer TreatmentWilson et al.NCI
11Vaccinia Virus Vector Used in Biologicals/VaccinesMoss et al.NIAID
12AIDS Drug ddIMitsuya et al.NCI
14Synthetic Thyrotropin as Adjuvant in Thyroid CancerWondisford et al.NIDDK
15Palifermin for Treatment of Oral MucositisRubin et al.NCI
 
 
photo: human puzzle with stethoscopeDIAGNOSTICS
Rank   
5Serological Detection of Antibodies and Nucleic Acid Detection of HIV-1Gallo et al.NCI
8DNA Probe for Breast Cancer DiagnosisKing et al.NCI
10Genoyping of HIV Protease GeneOroszlan et al.NCI
13Breast and Ovarian Cancer Screening Test (BRAC-1)Wiseman et al.NIEHS
19Diagnostic for Norwalk-like VirusGreen et al.NIAID
 
 
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
Rank   
7Diffusion Tensor Magnetic Resonance ImagingBasser et al.NICHD
18Digital PCR Method and AssemblySilver et al.NIAID
20Laser Capture MicrodissectionLiotta et al.NCI
 
 
photo: laboratory glasswareRESEARCH MATERIALS
Rank   
16Neutrophil Chemotactic Factor (IL-8)Matsushima et al.NCI
17Purified Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI