FY-2011 Top 20 Commercially Successful Inventions
(based on royalties on product sales)
VACCINES & THERAPEUTICS | |||
Rank | |||
1 | Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 | Erickson et al. | NCI |
2 | HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins | Lowy et al. | NCI |
3 | Monoclonal Antibody for Treatment of RSV | Murphy et al. | NIAID |
4 | Proteosome Inhibitor for Treatment of Multiple Myeloma | Gupta et al. | NCI |
6 | Nutritional Supplement to Treat Macular Degeneration | Ferris et al. | NEI |
9 | Paclitaxel as a Cancer Treatment | Wilson et al. | NCI |
11 | Vaccinia Virus Vector Used in Biologicals/Vaccines | Moss et al. | NIAID |
12 | AIDS Drug ddI | Mitsuya et al. | NCI |
14 | Synthetic Thyrotropin as Adjuvant in Thyroid Cancer | Wondisford et al. | NIDDK |
15 | Palifermin for Treatment of Oral Mucositis | Rubin et al. | NCI |
DIAGNOSTICS | |||
Rank | |||
5 | Serological Detection of Antibodies and Nucleic Acid Detection of HIV-1 | Gallo et al. | NCI |
8 | DNA Probe for Breast Cancer Diagnosis | King et al. | NCI |
10 | Genoyping of HIV Protease Gene | Oroszlan et al. | NCI |
13 | Breast and Ovarian Cancer Screening Test (BRAC-1) | Wiseman et al. | NIEHS |
19 | Diagnostic for Norwalk-like Virus | Green et al. | NIAID |
INSTRUMENTATION & DEVICES | |||
Rank | |||
7 | Diffusion Tensor Magnetic Resonance Imaging | Basser et al. | NICHD |
18 | Digital PCR Method and Assembly | Silver et al. | NIAID |
20 | Laser Capture Microdissection | Liotta et al. | NCI |
RESEARCH MATERIALS | |||
Rank | |||
16 | Neutrophil Chemotactic Factor (IL-8) | Matsushima et al. | NCI |
17 | Purified Transforming Growth Factor Beta (TGF-beta) | Sporn et al. | NCI |