FY-2009 Top 20 Commercially Successful Inventions
(based on royalties on product sales)
VACCINES & THERAPEUTICS | |||
Rank | |||
1 | HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins | Lowy et al. | NCI |
2 | Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 | Erickson et al. | NCI |
3 | Monoclonal Antibody for Treatment of RSV | Murphy et al. | NIAID |
4 | Synthetic Thyrotropin as Adjuvant in Thyroid Cancer | Wondisford et al. | NIDDK |
5 | Proteosome Inhibitor for Treatment of Multiple Myeloma | Gupta et al. | NCI |
7 | AIDS Drug ddI | Mitsuya et al. | NCI |
8 | Nutritional Supplement to Treat Macular Degeneration | Ferris et al. | NEI |
11 | Paclitaxel as a Cancer Treatment | Wilson et al. | NCI |
13 | Vaccinia Virus Vector Used in Veterinary Biologicals/Vaccines | Moss et al. | NIAID |
17 | Radioimmunotherapy for Non-Hodgkin's Lymphoma | Gansow et al. | NCI |
DIAGNOSTICS | |||
Rank | |||
9 | Serological Detection of Antibodies to HIV-1 | Gallo et al. | NCI |
10 | DNA Probe for Breast Cancer Diagnosis | King et al. | NCI |
14 | Genoyping of HIV Protease Gene | Oroszlan et al. | NCI |
18 | Norwalk Virus - IVD Product | Green et al. | NIAID |
INSTRUMENTATION & DEVICES | |||
Rank | |||
6 | Paclitaxel-Eluting Coronary Stent System | Kinsella et al. | NIA |
12 | Diffusion Tensor Magnetic Resonance Imaging | Basser et al. | NICHD |
15 | Laser Capture Microdissection | Liotta et al. | NCI |
16 | Enhanced Magnetic Resonance Imaging Through Magnetization Transfer | Balaban et al. | NHLBI |
RESEARCH MATERIALS | |||
Rank | |||
19 | Purified Transforming Growth Factor Beta (TGF-beta) | Sporn et al. | NCI |
20 | Neutrophil Chemotactic Factor (IL-8) | Matsushima et al. | NCI |