FY-2009 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
Rank   
1HPV Vaccines Based Upon Recombinant Papillomavirus Capsid ProteinsLowy et al.NCI
2Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1Erickson et al.NCI
3Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
4Synthetic Thyrotropin as Adjuvant in Thyroid CancerWondisford et al.NIDDK
5Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
7AIDS Drug ddIMitsuya et al.NCI
8Nutritional Supplement to Treat Macular DegenerationFerris et al.NEI
11Paclitaxel as a Cancer TreatmentWilson et al.NCI
13Vaccinia Virus Vector Used in Veterinary Biologicals/VaccinesMoss et al.NIAID
17Radioimmunotherapy for Non-Hodgkin's LymphomaGansow et al.NCI
 
 
photo: human puzzle with stethoscopeDIAGNOSTICS
Rank   
9Serological Detection of Antibodies to HIV-1Gallo et al.NCI
10DNA Probe for Breast Cancer DiagnosisKing et al.NCI
14Genoyping of HIV Protease GeneOroszlan et al.NCI
18Norwalk Virus - IVD ProductGreen et al.NIAID
 
 
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
Rank   
6Paclitaxel-Eluting Coronary Stent SystemKinsella et al.NIA
12Diffusion Tensor Magnetic Resonance ImagingBasser et al.NICHD
15Laser Capture MicrodissectionLiotta et al.NCI
16Enhanced Magnetic Resonance Imaging Through Magnetization TransferBalaban et al.NHLBI
 
 
photo: laboratory glasswareRESEARCH MATERIALS
Rank   
19Purified Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI
20Neutrophil Chemotactic Factor (IL-8)Matsushima et al.NCI