FY-2004 Top 20 Commercially Successful Inventions

(based on royalties on product sales)

photo: syringe, ampoulesVACCINES & THERAPEUTICS
Rank   
1Monoclonal Antibody for Treatment of RSVMurphy et al.NIAID
2AIDS Drug ddIMitsuya et al.NCI
4Paclitaxel as a Cancer TreatmentWilson et al.NCI
5Proteosome Inhibitor for Treatment of Multiple MyelomaGupta et al.NCI
7Synthetic Thyrotropin as Adjuvant in Thyroid CancerWondisford et al.NIDDK
8Nutritional Supplement to Treat Macular DegenerationFerris et al.NEI
9Hepatitis A Vaccine (Strain HM-175)Daemer et al. / Funkhouser et al.NIAID
13Radioimmunotherapy for Non-Hodgkin's LymphomaGansow et al.NCI
16AIDS Drug ddCMitsuya et al.NCI
 
 
photo: human puzzle with stethoscopeDIAGNOSTICS
Rank   
3Serological Detection of Antibodies to HIV-1Gallo et al. / Montagnier et al.NCI
12DNA Probe for Breast Cancer DiagnosisKing et al.NCI
14Genoyping of HIV Protease GeneOroszlan et al.NCI
15Serological Detection of Antibodies to HTLV-1Papas et al.NCI
 
 
abstract illustration: instrumentationINSTRUMENTATION & DEVICES
Rank   
6Paclitaxel-Eluting Coronary Stent SystemKinsella et al.NIA
10Enhanced Magnetic Resonance Imaging Through Magnetization TransferBalaban et al.NHLBI
11Laser Capture MicrodissectionLiotta et al.NCI
 
 
photo: laboratory glasswareRESEARCH MATERIALS
Rank   
17Reconstituted Basement MembraneKleinman et al.NIDCR
18Recombinant Cytochrome P-450Gelboin et al.NCI
19Transforming Growth Factor Beta (TGF-beta)Sporn et al.NCI
20Anthrax Protective AntigenLeppla et al.NIDCR