FY-2005 Top 20 Commercially Successful Inventions
(based on royalties on product sales)
VACCINES & THERAPEUTICS | |||
Rank | |||
2 | Monoclonal Antibody for Treatment of RSV | Murphy et al. | NIAID |
4 | AIDS Drug ddI | Mitsuya et al. | NCI |
5 | Paclitaxel as a Cancer Treatment | Wilson et al. | NCI |
6 | Synthetic Thyrotropin as Adjuvant in Thyroid Cancer | Wondisford et al. | NIDDK |
7 | Hepatitis A Vaccine (Strain HM-175) | Daemer et al. / Funkhouser et al. | NIAID |
8 | Nutritional Supplement to Treat Macular Degeneration | Ferris et al. | NEI |
9 | Radioimmunotherapy for Non-Hodgkin's Lymphoma | Gansow et al. | NCI |
10 | Proteosome Inhibitor for Treatment of Multiple Myeloma | Gupta et al. | NCI |
18 | AIDS Drug ddC | Mitsuya et al. | NCI |
DIAGNOSTICS | |||
Rank | |||
3 | Serological Detection of Antibodies to HIV-1 | Gallo et al. / Montagnier et al. | NCI |
12 | DNA Probe for Breast Cancer Diagnosis | King et al. | NCI |
13 | Genoyping of HIV Protease Gene | Oroszlan et al. | NCI |
15 | Serological Detection of Antibodies to HTLV-1 | Papas et al. | NCI |
INSTRUMENTATION & DEVICES | |||
Rank | |||
1 | Paclitaxel-Eluting Coronary Stent System | Kinsella et al. | NIA |
11 | Enhanced Magnetic Resonance Imaging Through Magnetization Transfer | Balaban et al. | NHLBI |
14 | Laser Capture Microdissection | Liotta et al. | NCI |
RESEARCH MATERIALS | |||
Rank | |||
16 | Reconstituted Basement Membrane | Kleinman et al. | NIDCR |
17 | Neutrophil Chemotactic Factor (Interleukin-8) | Matsushima et al. | NCI |
19 | Transforming Growth Factor Beta (TGF-beta) | Sporn et al. | NCI |
20 | Chemokine Receptors | Murphy et al. | NIAID |