FY-2016 Top 20 Commercially Successful Inventions
(based on royalties on product sales)
 | VACCINES & THERAPEUTICS | ||
| Rank | |||
| 1 | Novel Protease Inhibitor for Treatment of Drug-Resistant HIV-1 | Erickson et al. | NCI |
| 2 | HPV Vaccines Based Upon Recombinant Papillomavirus Capsid Proteins | Lowy et al. | NCI |
| 3 | Proteosome Inhibitor for Treatment of Multiple Myeloma | Gupta et al. | NCI |
| 4 | Nutritional Supplement to Treat Macular Degeneration | Ferris et al. | NEI |
| 9 | Palifermin for Treatment of Oral Mucositis | Rubin et al. | NCI |
| 11 | Vaccine for Dengue Virus | Lai et al. | NIAID |
| 18 | Development of Human Monoclonal Antibodies and Antibody Drug Conjugates Against CD276 as Cancer Diagnostics and Therapeutic Agents | Dimitrov et al. | NCI |
| 19 | Chimeric Antigen Receptors Targeting B-cell Maturation Antigen | Kochenderfer | NCI |
 | DIAGNOSTICS | ||
| Rank | |||
| 6 | DNA Probe for Breast Cancer Diagnosis (HER-2) | King et al. | NCI |
| 8 | Human Immunodeficiency Viruses Associated with AIDS, A Diagnostic Method for AIDS and Pre-AIDS, A Kit Therefor | Montagnier et al. | NCI |
| 14 | Process for Producing Monoclonal Antibodies Reactive with Human Breast Cancer | Schlom et al. | NCI |
| 16 | Parvovirus Capsids | Young et al. | NHLBI |
 | INSTRUMENTATION & DEVICES | ||
| Rank | |||
| 10 | Transcranial Magnetic Stimulation System | Zangen et al. | NIDA |
| 12 | Laser Capture Microdissection | Liotta et al. | NCI |
 | RESEARCH MATERIALS | ||
| Rank | |||
| 5 | Monoclonal Hybridoma Cell Lines | Murphy et al. | NIAID |
| 7 | Digital PCR | Silver et al. | NIAID |
| 13 | Monoclonal Antibody Reactive with Human Breast Cancer (TAG72) | Schlom et al. | NCI |
| 15 | Cloning, Expression and Diagnosis of Human Cytochrome P450 2C19 | Goldstein et al. | NIEHS |
| 17 | Mouse Expressing Enhanced Signaling for Bone Morphogenetic Protein (BMP): A Model For Human Disease | Mishina et al. | NIEHS |
| 20 | Synthetic Peptides for the Production of Specific Keratin Protein Antibodies | Yuspa et al. | NCI |