Technology ID
TAB-3693

Development of a Polyclonal Antibody for SAP102 and a Polyclonal Antibody for mGluR7 PS862

E-Numbers
E-003-2015-0
Lead Inventor
Roche, Katherine (National Institute of Neurological Disorders and Stroke)
Co-Inventors
Badger, John (National Institute of Neurological Disorders and Stroke)
Applications
Research Materials
Therapeutic Areas
Neurology
Immunology
Research Products
Antibodies
Lead IC
NINDS
This invention includes the generation and use of a polyclonal antibody for synapse-associated protein 102 (SAP102) and a polyclonal antibody that binds to mGluR7 when phosphorylated at Serine 862. Peptides of the sites were generated and injected into rabbits to create an immune response. Serum was collected from the rabbits that was then affinity purified. The specificity of the resulting polyclonal antibodies was then determined using biochemical techniques.
Commercial Applications
They will be used in laboratories as a tool for studying SAP102 and phosphorylated GluR7. They will be used in laboratories as a tool for studying SAP102 and phosphorylated GluR7.

Competitive Advantages
These antibodies are specific to these sites and can be used to detect phosphorylation of the amino acid at this specific site.

Request More Info

Licensing Contact:
Sharma, Smita
smita.sharma@nih.gov

Publications

  • Young HS, Pelkey KA, et al.
  • Chen B-S, Thomas EV, et al.
  • This record was updated as part of a batch update by the OTT team. The Owner of this record was updated from ‘Admin’ to the Licensing Contact listed on the record on 7/25/2024. If you have any questions or concerns, please reach out to ETT Support.
Date Published