Technology ID
TAB-1160

Monoclonal Antibody to the Protein NCOA6 (also called ASC-2, AIB-3)

E-Numbers
E-168-2005-0
Co-Inventors
Meltzer, Paul
Applications
Research Materials
Therapeutic Areas
Oncology
Lead IC
NHGRI
The invention relates to monoclonal antibodies that bind to the transcription factor NCOA6 (ASC-2, AIB-3, TRB, TRAP250, NRC). The antibodies have proven successful reagents for Western blotting and for purifying complexes containing NCOA6. The Western blot experiments revealed that NCOA6 is over-expressed in several breast cancer cell lines, and the purification experiments identified a protein complex containing NCOA6 (the ASCOM complex). The monoclonal antibodies may be useful reagents for studying the role of NCOA6 in transcription and for studying the ASCOM complex.

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Licensing Contact:
Campbell, Eggerton
eggerton.campbell@nih.gov

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  • In addition to licensing, the technology is available for further development through collaborative research opportunities with the inventors.
Date Published