Technology ID
TAB-2875

A Current Amplifier for Local Coil Pre-amplification of NMR/MRI Signals

E-Numbers
E-122-2014-0
Lead Inventor
Murphy-Boesch, Joseph (National Institute of Neurological Disorders and Stroke)
Co-Inventors
Dodd, Stephen (National Institute of Neurological Disorders and Stroke)
Koretsky, Alan (National Institute of Neurological Disorders and Stroke)
Qian, Chunqi (National Institute of Neurological Disorders and Stroke)
Applications
Software / Apps
Research Materials
Occupational Safety and Health
Non-Medical Devices
Medical Devices
Diagnostics
Therapeutic Areas
Oncology
Development Stages
Pre-Clinical (in vitro)
Development Status
  • In vitro data available
  • In vivo data available (animal)
Lead IC
NINDS
The magnetic resonance imaging (MRI) systems are used for a variety of imaging application. The present invention discloses an improving MRI device and method by amplifying signals received by resonant NMR coils of MRI systems. It utilizes positive feedback from low-noise Field-Effect Transistor to amplify the signal current that can be coupled out to receiving loops positioned externally without loss in sensitivity. Therefore, the NMR coil can be flexibly positioned near internal tissues and used to develop high-resolution images in highly invasive situations. The disclosed device can be developed in kit form as integrated modules that are designed to be added to tuned NMR receiver coils and tailored to deliver specific gains at NMR frequencies.
Commercial Applications
  • Medical and scientific research
  • Device for diagnostic
Competitive Advantages
  • Sensitivity
  • Easy to be integrated into the existed device

Request More Info

Licensing Contact:
Ano, Susan
susan.ano@nih.gov

Patents

  • US Patent 10,393,831
    Filed on 2016-11-07
  • US
    Provisional (PRV) 61/989,795
    Filed on 2014-05-07
  • Patent Cooperation Treaty
    (PCT) PCT/US2015/029674
    Filed on 2015-05-07

Publications

Collaborations

  • Collaboration

Collaboration Description

  • The National Institute of Neurological Disorders and Stroke, Laboratory for Functional and Molecular Imaging, is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate or commercialize a surgically implantable NMR detector, battery powered, for imaging of the pituitary. For collaboration opportunities, please contact Joseph Murphy-Boesch at murphyboeschj@mail.nih.gov.
Date Published