Technology ID
TAB-393
Method Of Identifying Inhibitors Of The Jak-STAT Signal Transduction Pathway
E-Numbers
E-176-1995-0
Co-Inventors
Leonard, Warren
Applications
Therapeutics
Research Materials
Diagnostics
Lead IC
NHLBI
The invention provides identification methods for agents which inhibit the Jak-STAT signaling transduction pathway. Drugs identified by these methods are candidates for the treatment of proliferative disorders dependent on the Jak-STAT pathway, including those caused by HTLV-1. In addition, such agents may be potent immunosuppressive drugs with potential applications not only for organ transplantation but also for treatment of autoimmune diseases.
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