Technology ID
TAB-3779
Monoclonal Antibody Against Human Alpha-5 Integrin that Does Not Disrupt Adhesive Function
E-Numbers
E-016-2017-0
Lead Inventor
Yamada, Kenneth (NIDCR)
Co-Inventors
Akiyama, Steven
Yamada, Susan (NIDCR)
Applications
Research Materials
Therapeutic Areas
Immunology
Research Products
Antibodies
Lead IC
NIDCR
ICs
NIDCR
This technology includes a rat monoclonal antibody termed mAb11 was generated against the human alpha-5 integrin subunit and can provide immunological characterizations without disrupting integrin adhesive function. It permits characterization of its localization even if the receptor is bound to its fibronectin ligand. The antibody is commercially available from Millipore Sigma.
Commercial Applications
Antibody characterization of the alpha-5/beta-1 integrin receptor for fibronectin.
Competitive Advantages
Because it is a rat monoclonal antibody, it permits co-staining using a mouse monoclonal antibody using indirect immunofluorescence.
Licensing Contact: