Technology ID
TAB-4545
Transcatheter MRI-guided Implantable Cavopulmonary Bypass Endograft for the Treatment of Congenital Heart Disease
E-Numbers
E-287-2015-0
Lead Inventor
MacDonald, Stuart (Transmural Systems, LLC)
Co-Inventors
Rafiee, Nasser (Mehr Medical)
Lederman, Robert (NHLBI)
Ratnayaka, Kanishka (Rady Children's Hospital, San Diego)
Applications
Medical Devices
Therapeutic Areas
Cardiology
Development Stages
Pre-clinical (in vivo)
Research Products
Research Equipment
Lead IC
NHLBI
ICs
NHLBI
This technology includes a catheter-delivered endograft designed to treat congenital heart disease without surgery. The specific surgical procedure averted is cavopulmonary bypass graft. The key innovations are features to effect distal end-to-side anastomosis and proximal end-to-end anastomosis without surgery. The system operates under X-ray and MRI guidance.
Commercial Applications
This endograft is specifically designed for congenital heart disease and may have applications for other bypass graft alternatives such as portal, visceral, and peripheral vascular such as carotid-subclavian to support thoracic aortic endograft.
Competitive Advantages
Transcatheter endografts have long been proposed and frequently have failed, however, this successful, simple transcatheter endograft anastomosis based on unique strut and flange design.
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